Evaluation of the Appropriateness of Thyroid Fine-Needle Aspiration

Authors

  • Lairce Brito FAHESP-IESVAP
  • Iara Botêlho FAHESP-IESVAP
  • Lanna Matos FAHESP-IESVAP
  • Nayse Aldeman FAHESP-IESVAP
  • Uziel Nunes FAHESP-IESVAP

DOI:

https://doi.org/10.31686/ijier.vol11.iss6.4127

Keywords:

thyroid nodule, fine needle biopsy, thyroid, liquid-based cytology, molecular testing

Abstract

This study aims to perform an integrative literature review on FNAB of the thyroid and its current contributions facing thyroid nodules, as an important diagnostic tool to eliminate early thyroid cancer, a recurrent pathology in offices. Regarding the methods, because this is an integrative review of literature, through a descriptive study, we used databases such as Medical Literature Analysis and Retrieval System Online (Medline/PubMed), Scientific Electronic Library Online (SciELO) and Virtual Health Library (VHL). The query was performed using the controlled descriptors from DeCS/MeSH: "thyroid nodule", "fine needle biopsy", "thyroid", "liquid-based cytology", "molecular test". Moreover, as a result we obtained a general review about the appropriateness of FNAB of the thyroid, an efficient and reliable diagnostic method in the decision and selection of patients who will need surgery. However, this method presents some limitations, such as the need for improvement in the quality of the sample collection or in its interpretation, limitations that can be reduced, decreasing the cases of false positives and negatives, when collected by experienced professionals, guided by ultrasound, and can be combined with color Doppler, as well as, seek opinions from other specialists. The present study also addressed the new diagnostic methods for thyroid nodules, such as liquid-based cytology, used as a technique in conjunction with conventional smears when ancillary techniques are applied, and molecular tests, which have given professionals the opportunity to provide a more accurate evaluation in cases of indeterminate nodules. With this, we reiterate the importance of identifying the best individualized strategy for the patient, preventing unnecessary procedures and offering improved quality of life.

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Author Biography

  • Lairce Brito, FAHESP-IESVAP

    Medical Student

References

Angell, T. E. (2019). Getting more out of molecular testing for indeterminate thyroid nodules. Cancer Cytopathology, 127(9), 555-556. DOI: https://doi.org/10.1002/cncy.22129

Brites, C. A., Balsimelli, L., Coelho, K. M., Fronza-Júnior, H., Stall, J., & França, P. H. C. (2018). Investigation of correlation between cytological and histological findings in suspected carcinoma of thyroid. Jornal Brasileiro de Patologia e Medicina Laboratorial, 54, 407-411. DOI: https://doi.org/10.5935/1676-2444.20180061

Cordes, M., Schmidkonz, C., Horstrup, K., Weppler, M., & Kuwert, T. (2018). Fine-needle aspiration biopsies of thyroid nodules. Nuklearmedizin-NuclearMedicine, 57(06), 211-215. DOI: https://doi.org/10.3413/Nukmed-0981-18-06

Filho, G. B. (2016). Bogliolo - Patologia geral (6a ed.). Guanabara Koogan.

Forneiro, M., Vieira, J. D. S. C., Dibo, M. V., & Santoro, F. G. (2022). Abordagem do nódulo de tireoide. Medicina, Ciência e Arte, 1(1), 92-101.

Foroughi, A. A., Mokhtari, M., Heidari, E., Nazeri, M., Rastgouyan, H., & Babaei, A. (2022). Concordance between TIRADS and Cytology in Thyroid Nodule. Iranian Journal of Otorhinolaryngology, 34(6).

Grani, G., Sponziello, M., Pecce, V., Ramundo, V., & Durante, C. (2020). Contemporary thyroid nodule evaluation and management. The Journal of Clinical Endocrinology & Metabolism, 105(9), 2869-2883. DOI: https://doi.org/10.1210/clinem/dgaa322

Guindan, P. M., Palacios Cointte, J. E., Rubino, A., Pujadas Bigi, M., & González Calderón, J. (2022). Valor de la PAAF y el Sistema Bethesda en tumores de tiroides. Prensa méd. argent, 194-200.

Joo, L., Lee, M. K., Lee, J. Y., Ha, E. J., & Na, D. G. (2023). Diagnostic performance of ultrasound-based risk stratification systems for thyroid nodules: a systematic review and meta-analysis. Endocrinology and Metabolism, 38(1), 117-128. DOI: https://doi.org/10.3803/EnM.2023.1670

Kant, R., Davis, A., & Verma, V. (2020). Thyroid Nodules: Advances in Evaluation and Management. American family physician, 102(5), 298–304.

Mahajan, S., Rajwanshi, A., Srinivasan, R., Radotra, B. D., & Panda, N. (2021). Should liquid based cytology (LBC) be applied to thyroid fine needle aspiration cytology samples?: comparative analysis of conventional and LBC smears. Journal of Cytology, 38(4), 198. DOI: https://doi.org/10.4103/JOC.JOC_6_17

Makde, M. M., & Sathawane, P. (2022). Liquid-based cytology: Technical aspects. CytoJournal, 19. DOI: https://doi.org/10.25259/CMAS_03_16_2021

Morais, O. L., Vieira, G. C. F., Botelho, A. C. L. M., Lacerda, E. A., Nunes, É. J. G., Silva, L. P., ... & Braga, A. C. C. (2019). Nódulos tireoidianos–uma abordagem diagnóstica. Revista Eletrônica Acervo Saúde, (23), e402-e402. DOI: https://doi.org/10.25248/reas.e402.2019

Nishino, M., & Nikiforova, M. (2018). Update on molecular testing for cytologically indeterminate thyroid nodules. Archives of Pathology & Laboratory Medicine, 142(4), 446-457. DOI: https://doi.org/10.5858/arpa.2017-0174-RA

Núñez, E. R., & Vela, R. Á. M. (2019). Eficiencia de la punción por aspiración con aguja fina en el diagnóstico de las afecciones del tiroides. Revista Información Científica, 98(5), 577-586. DOI: https://doi.org/10.22529/me.2020.5(2)02

Pantanowitz, L., Thompson, L. D., Jing, X., & Rossi, E. D. (2020). Is thyroid core needle biopsy a valid compliment to fine-needle aspiration?. Journal of the American Society of Cytopathology, 9(5), 383-388. DOI: https://doi.org/10.1016/j.jasc.2020.06.003

Park, J. Y., Choi, W., Hong, A. R., Yoon, J. H., Kim, H. K., & Kang, H. C. (2023). A comprehensive assessment of the harms of fine-needle aspiration biopsy for thyroid nodules: a systematic review. Endocrinology and Metabolism, 38(1), 104-116. DOI: https://doi.org/10.3803/EnM.2023.1669

Patel, J., Klopper, J., & Cottrill, E. E. (2023). Molecular diagnostics in the evaluation of thyroid nodules: Current use and prospective opportunities. Frontiers in endocrinology, 14, 1101410. DOI: https://doi.org/10.3389/fendo.2023.1101410

Patel, S. G., Carty, S. E., & Lee, A. J. (2021). Molecular testing for thyroid nodules including its interpretation and use in clinical practice. Annals of Surgical Oncology, 1-8. DOI: https://doi.org/10.1245/s10434-021-10307-4

Pinto-Blázquez, J., & Ursúa-Sarmiento, I. (2020). Anatomía patológica de la patología de tiroides y paratiroides. Sistema Bethesda del diagnóstico citológico de la patología de tiroides. Revista ORL, 11(3), 259-264. DOI: https://doi.org/10.14201/orl.21596

Poller, D. N., Johnson, S. J., & Bongiovanni, M. (2020). Measures to reduce diagnostic error and improve clinical decision making in thyroid FNA aspiration cytology: A proposed framework. Cancer Cytopathology, 128(12), 917-927. DOI: https://doi.org/10.1002/cncy.22309

Porto, C.C. (2019). Semiologia Médica (8ª ed.). Guanabara Koogan.

Rodríguez-González, M., González-Velasco, C., Gómez-Muñoz, M. A., Sayagués-Manzano, J. M., & Ludeña-de-La-Cruz, M. D. (2021). Cómo mejorar la precisión de los diagnósticos I y III del Sistema Bethesda. Revista ORL, 12(4), 313-323. DOI: https://doi.org/10.14201/orl.25005

Ross, D. S. (2021). Laboratory assessment of thyroid function. UpToDate, Cooper, DS (Ed), UpToDate, Waltham, MA.

Ross, D. S., Cooper, D. S., & Mulder, J. E. (2020). Diagnostic approach to and treatment of thyroid nodules. UpToDate, Waltham, MA.

Ross, D. S., Cooper, D. S., & Mulder, J. E. (2020). Evaluation and management of thyroid nodules with indeterminate cytology. UpToDate, Waltham, MA.

Ross, D. S., Cooper, D., & Mulder, J. (2022). Thyroid biopsy. UpToDate, Waltham, MA.

Sayer, A. O., Mut, D. T., Von Bodelschwingh, B., Ozguven, B. Y., & Sahin, C. (2022). Comparison of Conventional Smear and Liquid-Based Cytology in Adequacy of Thyroid Fine-Needle Aspiration Biopsies without an Accompanying Cytopathologist. The Medical Bulletin of Sisli Etfal Hospital, 56(3), 353.

Sharma, R., Zaheer, S., & Ahluwalia, C. (2022). Diagnostic utility of conventional and liquid-based cytology in the management of thyroid lesions; an institutional experience. CytoJournal, 19. DOI: https://doi.org/10.25259/Cytojournal_34_2021

Sharma, S., Agarwal, S., Jain, M., Singh, G. B., & Andley, M. (2018). Cytomorphological differences between liquid-based cytology and conventional smears in fine-needle aspirates of thyroid lesions. Journal of Cytology, 35(4), 208. DOI: https://doi.org/10.4103/JOC.JOC_150_17

Silva, I. O, & Ferreira, A. M. (2019). Associação das características ecográficas de nódulos tireoideanos com os achados citológicos. Jornal de Ciências da Saúde do Hospital Universitário da Universidade Federal do Piauí, 2(3), 38-50. DOI: https://doi.org/10.26694/jcs_hu-ufpi.v2i3.11997

Silveira, E. L. L., & Silveira, Y. S. (2018). Perfil Clínico e Citopatológico Contido em Amostras de Punção Aspirativa por Agulha Fina de Nódulos Tireoidianos. Revista de Patologia do Tocantins, 5(3), 18-23. DOI: https://doi.org/10.20873/uft.2446-6492.2018v5n3p18

Ucak, R., Eryilmaz, O. T., Ozguven, B. Y., Uludag, M., & Kabukcuoǧlu, F. (2021). Evaluation of thyroid fine-needle aspiration biopsies according to cytological methods and comparison with histopathological diagnosis. Şişli Etfal Hastanesi Tip Bülteni, 55(1), 93-100. DOI: https://doi.org/10.14744/SEMB.2020.94752

Vilela, E. F., & Carvalho, M. S. (2019). Modelo ambulatorial de atendimento de nódulo de tireoide. Revista da Sociedade Brasileira de Clínica Médica, 17(2), 113-117.

Wang, M., Wang, X., & Zhang, H. (2022). Grayscale, subjective color Doppler, combined grayscale with subjective color Doppler in predicting thyroid carcinoma: a retrospective analysis. Brazilian Journal of Otorhinolaryngology, 88, 220-227. DOI: https://doi.org/10.1016/j.bjorl.2020.05.024

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Published

2023-06-01

How to Cite

Brito, L. C. R., De Carvalho Botêlho, I. B., Silva Fernandes, L. M., Sangreman Aldeman, N. L., & Nunes Silva, U. (2023). Evaluation of the Appropriateness of Thyroid Fine-Needle Aspiration. International Journal for Innovation Education and Research, 11(6), 8-24. https://doi.org/10.31686/ijier.vol11.iss6.4127
Received 2023-05-19
Accepted 2023-07-18
Published 2023-06-01