Review of Clinical Factors That Cause Acne Vulgaris

Authors

  • Zípora Santos Universidade Franciscana
  • Maiara Velho Universidade Franciscana
  • Fátima Zan Instituto Federal Farroupilha, Santo Ângelo, Brazil.
  • Virgínia Rech Universidade Franciscana
  • Aline Ferreira Ourique Universidade Franciscana

DOI:

https://doi.org/10.31686/ijier.vol8.iss9.2659

Keywords:

skin disorder, pilosebaceous follicle, etiopathogenesis, pathophysiology

Abstract

Acne vulgaris is a common skin disorder caused by inflammation and/or blockage of the pilosebaceous follicle. This research is a literature review study that is descriptive in nature and seeks to compile information on the factors related to the etiopathogenesis of the clinical manifestations of acne vulgaris. A survey was conducted in the Web of Science database in the period from January to May 2019, using the keywords "acne vulgaris, etiopathogenesis and pathophysiology". The etiopathogenesis of acne vulgaris is multifactorial, but most studies list the following factors: like diet, daily habits, age, genetics, abnormalities in the production of sebum, follicular hyperkeratinization, increased colonization by Cutibacterium (formerly Probionibacterium) acnes, periglandular dermal inflammation, oxidative stress and immune reactions of the patient. Topical and/or systemic treatments for acne vulgaris, often includes retinoid-associated antibiotics. However, improper use of these can lead to bacterial resistance, in addition, it may trigger adverse effects at epidermis and dermis. The results obtained in this study are important in relation to the treatment of the pathogenesis of acne vulgaris. It is believed that this information - when analyzed together - can help with a better definition of the therapeutic protocol.

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Author Biographies

  • Zípora Santos, Universidade Franciscana

    Laboratory of Nanotechnology

  • Maiara Velho, Universidade Franciscana

    Laboratory of Nanotechnology

  • Fátima Zan, Instituto Federal Farroupilha, Santo Ângelo, Brazil.

    Innovation and Technology Transfer Center

  • Virgínia Rech, Universidade Franciscana

    Laboratory of Nanotechnology

  • Aline Ferreira Ourique, Universidade Franciscana

    Professor Graduate Program in Nanosciences

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Published

2020-09-01

How to Cite

Santos, Z., Velho, M., Zan, F., Rech, V., & Ferreira Ourique, A. (2020). Review of Clinical Factors That Cause Acne Vulgaris. International Journal for Innovation Education and Research, 8(9), 434-447. https://doi.org/10.31686/ijier.vol8.iss9.2659