Antihypertensive and hematological effects of Tribulus terrestris Aqueous Extract
DOI:
https://doi.org/10.31686/ijier.vol3.iss8.410Keywords:
Plant, hypertension, blood constituentAbstract
The effect of 100 and 50 mg/kg body weight Tribulus terrestris aqueous extract at on the cardiovascular system of rats was studied. Initial heart rate of 160, systolic100 & diastolic 40was considered as normal pressure.. One minute after extract administration the blood pressure and heart rate of rats were raised. The rats' blood pressure continued in a remarkable increasing manner reaching a 180 systolic, 150 diastolic mm/Hg and the heart rate beat were 200, no mortality was observed. Perfusion pressure was raised with the aqueous extract administration then reduced to the normal level after 90 minutes. It was concluded that aqueous extracts of Tribulus terrestris possess significant hypotensive activity in hypertensive rats. The hypotensive effects of Tribulus terrestris appeared may be due to the direct arterial smooth muscle contraction and membrane hypo polarization. These results suggested the curative effect of T. terrestris aqueous extract on hypertensive animals.
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