Cell death and its relationship to viral infections: What are the ways to fight viruses?

Gabriella Brandimarte Queiroz; Carla Catarina Silva; Augusto Alberto Foggiato; Juliana Zorzi Coléte; João Lopes Toledo Neto; Fabrício José Jassi; Douglas Fernandes da Silva

doi:10.31686/ijier.vol9.iss3.2991

Authors

Gabriella Brandimarte Queiroz University of the State of Paraná
Carla Catarina Silva University of the State of Paraná
Augusto Alberto Foggiato University of the State of Paraná
Juliana Zorzi Coléte University of the State of Paraná
João Lopes Toledo Neto University of the State of Paraná
Fabrício José Jassi Universidade de São Paulo
Douglas Fernandes da Silva Sao Paulo State University

DOI:

https://doi.org/10.31686/ijier.vol9.iss3.2991

Keywords:

Apoptosis, Necrosis, Autophagy, Virus

Abstract

Cell death is a crucial process for maintaining homeostasis and the development of the organism. They are mainly characterized by apoptosis, necrosis and autophagy, being complex processes and essences for the immune system and balance of the human organism, especially when there are infectious agents such as viruses. Therefore, a bibliographic review was carried out seeking to deepen the knowledge of cell death applied to viruses, and its possible action against COVID-19, demonstrating the action and importance of understanding and understanding cell death pathways and applying their results as therapeutic targets. The results obtained showed the individual action of cell deaths against the virus in the immune system and emphasized the understanding of cell death pathways as fundamental for the development of drugs and therapies for viral control for already known viruses and for new viruses, such as Covid -19.

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Author Biographies

Gabriella Brandimarte Queiroz, University of the State of Paraná

Graduate student in dentistry
Carla Catarina Silva, University of the State of Paraná

Graduate student in dentistry
Augusto Alberto Foggiato, University of the State of Paraná

Dentist, Specialist in Radiology, Orthodontics and Facial Orthopedics, Ms and PhD OrthodonticsHealth Sciences Center -Dentistry
Juliana Zorzi Coléte, University of the State of Paraná

Dentist, DDS, MSc, PhD, Post-doc on Oral & Maxillofacial Surgery and Implantology, Health Sciences Center - Dentistry
João Lopes Toledo Neto, University of the State of Paraná

Dentist and PhD of oral-biology by the Faculty of Dentistry of Piracicaba Unicamp, Health Sciences Center
Fabrício José Jassi, Universidade de São Paulo

Physiotherapist and PhD rehabilitation and functional performance - School of Physical Education and Sport of Ribeirão Preto
Douglas Fernandes da Silva, Sao Paulo State University

Biologist, biotechnological engineer and PhD in applied microbiology

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