Basal cell carcinoma - epidemiology, pathogenesis, pathology, and association with inflammation biomarkers. A review 116 544
DOI:
https://doi.org/10.31686/ijier.vol8.iss3.2226Keywords:
basal cell carcinoma, epidemiology, pathology, biomarkers, inflammationAbstract
Basal cell carcinoma is the most common malignant neoplasm in humans, with low mortality, high morbidity, and exposure to solar radiation (UVB and UVA) is the most critical risk factor. Ultraviolet B rays generate mutagenic photoproducts in DNA and mutations in important genes regulating cellular functions, such as the tumor suppressor gene TP53. Ultraviolet A rays generate cytotoxic and mutagenic free radicals, potentiating the effects of UVB rays.. There is current evidence to support the role of inflammatory biomarkers related to tumorigenesis of basal cell carcinoma.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Rondon Ramalho, Takita, Cesar, Marcel, Gabriely, Gunter Hans, Rondon, Ricardo Aydos
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Copyrights for articles published in IJIER journals are retained by the authors, with first publication rights granted to the journal. The journal/publisher is not responsible for subsequent uses of the work. It is the author's responsibility to bring an infringement action if so desired by the author for more visit Copyright & License.
